Cresol Red – Thymol Blue, Aqueous . Skin Contact Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Company Identification: LabChem Inc . Company Phone Number: (412) 826-5230 . P-Cresol | CH3C6H4OH or C7H8O | CID 2879 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Get medical attention. It is useful as a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8. Give a pH range for this solution. What color is a solution of 0.10 M NaOH when 1 drop of cresol purple is added? The Occupational Safety and Health Administration has set a permissible exposure limit at 5 ppm (22 mg/m3) over an eight-hour time-weighted average, while the National Institute for Occupational Safety and Health recommends a limit of 2.3 ppm (10 mg/m3). Formocresol, a preparation of formalin and cresol, is also used as a root canal medicament and for pulpotomy of primary teeth. In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. 7732-18-5 >99 ; Water . Product identifier . Chemical structure. Cresol Red Revision Date 18-Jan-2018 Cresol red 1733-12-6 100 4. Cresol Red, 0.04% Aqueous Safety Data Sheet according to Federal Register / Vol. Get the latest public health information from CDC: https://www.coronavirus.gov. Emergency Phone Number: (800) 424-9300 . soln. ; Cresol Red sodium salt, 0.04% w/v aq. Except where otherwise noted, data are given for materials in their standard state (at … Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, "Making carbon nanotubes as usable as common plastics: Researchers discover that cresols disperse carbon nanotubes at unprecedentedly high concentrations", "Additive-free carbon nanotube dispersions, pastes, gels, and doughs in cresols", Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs) - Cresol (o, m, p isomers), https://en.wikipedia.org/w/index.php?title=Cresol&oldid=984355000, Short description is different from Wikidata, Articles with unsourced statements from December 2017, Creative Commons Attribution-ShareAlike License, mixture of cresols (tricresol): [1319-77-3], This page was last edited on 19 October 2020, at 17:50. Contents. 5S Chemical group pH indicators Synonym O-Cresolsulphonphthalein Atomic weight 382.44 Weight per litre 0.98kg Appearance Reddish-brown crystalline powder. acids, and dil. Section 2 - Composition, Information on Ingredients. Beilstein/REAXYS Number 343399 . Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownish red tint. At what pH is cresol red, orange in color? Aside from these effects, very little is known about the effects of breathing cresols, for example, at lower levels over longer times. CAS# Chemical Name: Percent. 382.43. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. These antioxidants are valued because they are relatively low in toxicity and nonstaining. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Contributors. Cresol red indicator Reag. MSDS Name: Cresol Red – Thymol Blue, Aqueous . Ambient temperatures. Soluble in water, dilute alcohols, acids, alkalies and ethanol. Main ChemSpider page; Molecular formula: C 21 H 17 NaO 5 S; Molar mass: 404.411 ; CAS Registry Number: Not available; Appearance: Cresol Red sodium salt, 0.04% w/v aq. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Further, it plays an important role in molecular biology reactions in place of other loading dyes. soln. Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. 9. Bromophenol blue and xylene cyanol can also be used for this purpose. Another method entails methylation of phenol with methanol over a solid acid catalyst, often comprising magnesium oxide or alumina. Cresol Red, sodium salt, water soluble, indicator Revision Date 18-Jan-2018 13. 0. Its solubility is 0.77 grams per liter (g/l) in water and 2.9 g/l in ethanol . There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). Cresols (also hydroxytoluene) are organic compounds which are methylphenols. InChI=1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, InChI=1/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, Cc1cc(ccc1O)/C(=C/2C=CC(=O)C(=C2)C)c3ccccc3OS(O)=O, Except where otherwise noted, data are given for materials in their, Learn how and when to remove this template message, Cresol Red at OpenWetWare life scientists' wiki, https://en.wikipedia.org/w/index.php?title=Cresol_Red&oldid=966465054, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles lacking sources from September 2007, Creative Commons Attribution-ShareAlike License, This page was last edited on 7 July 2020, at 08:15. A solution is yellow when both methyl yellow and cresol purple are added. If you try to dissolve more than this, you get two layers of liquid. Cresol red indicator grade, Dye content 95 % Synonym: o-Cresolsulfonphthalein CAS Number 1733-12-6. Subject:* missing translation for 'pleaseEnterSubject'. Cresol red sodium salt can be used in many common molecular biology reactions in place of other loading dyes. 200 William Pitt Way . alkalis. Molecular Weight 382.43 . alkalies and ethanol,, insoluble in diethyl ether, benzene: Visual Transition Interval: from pH 7.0 (orange) to pH 8.8 (purple) Color: Brown-Red or Green : SDS. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. 200 William Pitt Way . 77, No. Solubility in water. Catalog Numbers: LC13540 . Cresol red does not inhibit Taq polymerase to the same degree as other common loading dyes. MW: 404.41 [9], Group of chemical compounds, types of methylphenol. room temp SMILES string [Na+].Cc1cc(ccc1O)\C(=C2/ C=CC(=O)C(C)=C2)c3ccccc3S ([O-])(=O)=O … They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). This is effective almost on all the microbes. Synonyms: None . ca 250° dec. [6], Most recently, cresols have been used to create a breakthrough in manufacturing carbon nanotubes at scale that are separated and not twisted, without additional chemicals that change the surface properties of the nanotubes.[7][8]. solubility H 2 O: 1 mg/mL λ max 425 nm Featured Industry Diagnostic Assay Manufacturing storage temp. H315, H319, H335: GHS precautionary statements. % in H 2 O CAS Number 1733-12-6. C 2 1 H 1 7 NaO 5 S. Formula Weight. Beilstein/REAXYS Number 343399 . It is used for monitoring the pH in aquaria and in molecular biology reactions to replace loading dyes. Cresol red solution 0.04 wt. 011-703-527-3887 . Helmut Fiegein "Cresols and Xylenols" in Ullmann's Encyclopedia of Industrial Chemistry" 2007; Wiley-VCH, Weinheim. Cresol Red Indicator Solution . 14. Formula. ChEBI. COVID-19 is an emerging, rapidly evolving situation. Properties. Anisole converts to cresols under these conditions. However, little is known about its effect on cardiovascular system. [1] It is a weak acid with p K a = 8.00 at 20 °C (68 °F). Cresol red can be used in many common molecular biology reactions in place of other loading dyes. Buy Cresol red sodium salt (CAS 62625-29-0), a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8, from Santa Cruz. MDL number MFCD00005878. No human or animal studies have shown harmful effects from cresols on reproduction. CAS Number. MDL number MFCD00001618 Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Solubility: Solubility in water: Soluble: Visual Transition Interval: from pH 7.0 (yellow) to pH 8.8 (purple) Color: Brown: Quantity: 5g: Chemical Name or Material: Cresol Red, sodium salt LabChem solutions u Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. Cresol Red sodium salt. Cresol red can also be used as an electrophoretic color marker to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis. 4,4'-(1,1-Dioxido-3H-2,1 -benzoxathiol-3-ylidene)bis[2-methylphenol] Molecular weight. Chemical Properties. Cresol Red, Indicator Grade, Pure, ACROS Organics™ ... Solubility: Solubility in water: soluble. The top layer is a solution of phenol in water, and the bottom one a solution of water in phenol. P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501: NFPA 704 (fire diamond) 0. Molecular formula. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Get medical attention. Phenol red exists as a red crystal that is stable in air. 1733-12-6 . Dissolve 60 g of sucrose in 80 ml distilled water on magnetic stirrer. 404.42 Melting point. Cresol Red, 0.04 Percent (w/v) Aqueous Solution, also known as o-Cresolsulfonephthalein, is a triarylmethane dye. The name cresol reflects their structure, being phenols, and their traditional source, creosote. Cresol red is a member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups. It has a role as an acid-base indicator, a dye and a two-colour indicator. Cresol red (sodium salt) Last updated; Save as PDF Page ID 75505; No headers. Cresol is a well-known environmental pollutant, toluene metabolite, uremic toxicant and accidental poisoning product. MDL. Back to Top. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. The rest is produced by hydrolysis of chlorotoluenes or the related sulfonates. Pittsburgh, PA 15238 . 1.1. Breathing high levels of cresols for a short time results in irritation of the nose and throat. Ingesting high levels results in kidney problems, mouth and throat burns, abdominal pain, vomiting, and effects on the blood and nervous system. 62625-29-0 : Cresol red… PubChem Substance ID 24847173 77, No. Cresol red stock buffer 60% sucrose 0.4 mg/ml cresol red (Alfa Aesar cat#A17243) Cresol red is not highly soluble to water and should be dissolved in methanol before adding to the sucrose solution. Phenol is somewhat soluble in water because of its ability to form hydrogen bonds with the water. When dissolveing cresol red, use only minimum amount of methanol. Storage & Sensitivity. Cresols (also hydroxytoluene) are organic compounds which are methylphenols. Soluble in water (slightly at 20°C), 50% ethanol (0.1%), dil. These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol. Solubility. Skin contact with high levels of cresols can burn the skin and damage the kidneys, liver, blood, brain, and lungs. acids, dil. Red solution Solubility Powder soluble in water, alcohol and dilute acids and alkalis. [5][6], Cresols are precursors or synthetic intermediates to other compounds and materials, including plastics, pesticides, pharmaceuticals, and dyes. Section 1 - Chemical Product and Company Identification . The spectrophotometric methods depend on the formation of chloroform-soluble ion-association complexes of cinnarizine with thymol blue (TB) and with cresol red in sodium acetate–acetic acid buffer of pH 3.6 for TB and in potassium chloride–hydrochloric acid buffer at pH 1.6 for cinnarizine with absorption maxima at 405 and 403 nm for TB and cinnarizine, respectively. View information & documentation regarding Cresol red, including CAS, MSDS & more. Emergency Phone Number: (800) 424-9300 . Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. Inhalation Remove from exposure, lie down. CHEMTREC … Temperatures above 300 °C are typical. MDL number MFCD00005878. Do not autoclave. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Revision date: 05/03/2017 Supersedes: 12/23/2014 Version: 1.1 05/03/2017 EN (English US) Page 1 SECTION 1: Identification 1.1. They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownis… Short-term and long-term studies with animals have shown similar effects from exposure to cresols. Applications. C 21 H 18 O 5 S. Storage instructions. Cresol Red does not inhibit Taq polymerase to the same degree as other common loading dyes. Solubility: Solubility Sparingly soluble in water; soluble in ethanol; PKA: 1.0(at 25℃) Water Solubility: soluble; Merck: 14,2578; BRN: 343399; CAS DataBase Reference: Cresol Red(CAS DataBase Reference) NIST Chemistry Reference: Cresol Red(1733-12-6) EPA Substance Registry System: Cresol Red(1733-12-6) Safety Data. 1. Chemical name. Sigma-Aldrich offers a number of Cresol red products. EC Number 217-064-2. CHEMTREC Phone Number: (800) 424-9300 or . MFCD00001618. When cresols are inhaled, ingested, or applied to the skin, they can be very harmful. [citation needed] About half of the world's supply of cresols are extracted from coal tar. Effects observed in people include irritation and burning of skin, eyes, mouth, and throat; abdominal pain and vomiting; heart damage; anemia; liver and kidney damage; facial paralysis; coma; and death. Company Phone Number: (412) 826-5230 . The monoalkylated derivatives undergo coupling to give an extensive family of diphenol antioxidants. In agarose, Cresol Red runs with an apparent molecular size of approximately 125 bp DNA. Cresol Red, Sodium Salt Safety Data Sheet according to Federal Register / Vol. Company Identification: LabChem Inc . It is not known what the effects are from long-term ingestion or skin contact with low levels of cresols. Store at Room Temperature. p-Cresol is consumed mainly in the production of antioxidants, such as butylated hydroxytoluene (BHT). Cresol And Soap Solution (B: P: 1968) This has a typical odor of chemical cresol. Cresols have an odor characteristic to that of other simple phenols, reminiscent to some of a "coal tar" smell. Cresol Red does not inhibit Taq polymerase. Phenol is moderately soluble in water - about 8 g of phenol will dissolve in 100 g of water. A 0.290 gram sample of a weak base is titrated with a 0.150 M HCl solution. Molecular Weight 382.43 . 263-654-8. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Version: 1.0 12/23/2014 EN (English US) Page 1 SECTION 1: Identification of the substance/mixture and of the company/undertaking . EC Index Number 217-064-2 It is a 2,1-benzoxathiole, an arenesulfonate ester, a polyphenol and a sultone. C and T manufactures Cresol and Soap solution according to bp1968 standards. EINECS. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Other solubilities: soluble in dil. Molecular Weight 382.43 . Pittsburgh, PA 15238 . In a 1% agarose gel, it runs approximately at the size of a 125 base pair (bp) DNA molecule (it depends on the concentration of buffer and other component). The mode of action of this disinfectant is to disrupt the … Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Ph Eur Synonym: Cresol red, o-Cresolsulfonphthalein CAS Number 1733-12-6. 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For pulpotomy of primary teeth breathing high levels of cresols can be solid or liquid because they are low! On reproduction of cresols can be very harmful λ max 425 nm Featured Diagnostic! Cas Number 1733-12-6 chemtrec Phone Number: ( 800 ) 424-9300 or bp DNA the bottom one a of! Pollutant, toluene metabolite, uremic toxicant and accidental poisoning product role in biology. ], group of aromatic organic compounds which are methylphenols No headers: GHS Signal word Warning... A molecule of cresol purple is added ethanol ( 0.1 % ), 50 % ethanol 0.1! Ph in aquaria or skin Contact with high levels of cresols for a short results. H335: GHS precautionary statements primary teeth more specifically, tricresol / Vol methanol over a solid acid,! '' smell bonds with the water 75505 ; No headers a methyl group substituted onto the ring phenol... Polyphenol and a sultone and damage the kidneys, liver, blood, brain, and traditional... As a red crystal that cresol red solubility stable in air ) 424-9300 or you get layers.: 1968 ) this has a methyl group substituted onto the ring of in! Soap solution according to bp1968 standards is not known what the effects are from long-term ingestion or skin Contact off!