The empiric medications most frequently used for refractory NMS include bromocriptine mesylate, a dopamine agonist, and dantrolene sodium, a muscle relaxant. Stopping the offending agent immediately, using systemic with tapering over 8 to 12 weeks, and topical, high-potency glucocorticoids can help. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Learn more. passive eruption. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. With the understanding that this infection is a complication of antimicrobial therapy, an important therapeutic intervention is discontinuation of the offending drug when possible (52). (Klaus MV, Wieselthier JS, Am Fam Physician 1993 Sep 15;48(4):629-632) offending definition: 1. unwanted, often because unpleasant and causing problems: 2. unwanted, often because unpleasant…. Simply discontinuing the offending agent may be the only intervention necessary in a small proportion of patients, generally those with mild infection (130). The rash usually burns, occurs on the face or the genitals, and, if the offending agent is given again, recurs in the same location. The film became notorious because it took £89 [1] or £79 [2] at the box office. Often they are considered gentle giants. Increased size of the clinical crown of a tooth by apical migration of the attachment epithelium and periodontium. 1,14,15 Quality of Life Working dogs are the canine muscle group: Malamutes, Portuguese Water Dogs, Saint Bernards, and Bernese Mountain Dogs. The offending scenes involved leading man Peter Weller and Kevin Page, who played the young executive that gets shot to ribbons during a botched demonstration of the ED-209 police robot. It was directed by Andrew Rajan and starred Susannah Harker , Shaun Parkes and Michael Cochrane . Treatment includes removal of the offending agent in conjunction with use of anti-inflammatory steroid creams, antihistamines and, in severe cases, oral corticosteroids. Offending Angels is a 2002 British romantic comedy film. See more. Diagnosis is suggested by the localization of the eruption and the history of exposure to an offending agent. defend definition: 1. to protect someone or something against attack or criticism; to speak in favour of someone or…. (transitive) To hurt the feelings of; to displease; to make angry; to insult. Learn more. How the situation is handled (and by that I mean whether or not you should be writing under two separate names and/or keeping the material on the web site) is going to depend on the market you’re targeting and how graphic the pieces might be. Offend definition, to irritate, annoy, or anger; cause resentful displeasure in: Even the hint of prejudice offends me. 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